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While Everything Else is Falling, These Stocks Are Soaring...
By Rob Fannon, editor, Phase 1 Investor
July 19, 2008

I love getting phone calls from my colleague Steve Sjuggerud. But often, I never have anything positive to say...

In the last two years, Steve has called me three separate times to talk about big drug stocks like Pfizer and Merck. I've given him the same advice each time... Stay away. And I don't think I'm going to tell him any different anytime soon.

As Steve wrote in a recent DailyWealth, Pfizer – the bellwether Big Pharma stock – is cheaper than it's been in recorded history, trading for less than 10 times forward earnings. And yes, the big drugmakers are "hated" – 97% of the population has an unfavorable view of the industry. Even lawyers and politicians rank higher on trustworthiness scales.
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But Big Pharma fails on Steve's third criteria for investment – an uptrend. The industry is facing just the opposite...

Pharmaceutical stocks are down 15% from their highs this year... and almost 20% from their 2007 peak. That's because the world's biggest drugmakers are racing off the side of a cliff – a patent cliff.

Patent protection is the moat in the drug industry. But unlike other competitive advantages, including brand name, the patent moat has a 20-year expiration date. Once a drug goes off patent, generic drugmakers flood the market with copycats. These copycats can destroy brand-name sales.

Last year, $16 billion worth of brand-name drugs went off patent. This figure will rise to more than $100 billion by 2011, as 70 of the 100 top-selling drugs in the business will lose patent. Pfizer stands to lose 50% of its $48 billion in annual sales to generic drugs within three years, when Lipitor, the world's top-selling drug, loses patent protection.

Drug development is a costly and risky business. It takes an average 10 years and $1 billion to bring a new drug to market. The failure rates are extraordinarily high. There's nothing Pfizer, Merck, or Bristol-Myers can do overnight to replace expiring patents... Or is there?

As Steve has mentioned, big drugmakers are replacing lost sales by cherry-picking new drugs from the biotech industry. Biotech drugs are harder to copy than traditional drugs, making them more expensive to produce and less prone to future competition from generics. So drugmakers are willing to pay up to get a few biotech drugs in the pipeline.

In April, for example, the biggest Japanese pharmaceutical company – Takeda Pharmaceuticals – paid close to $9 billion to acquire Millennium Pharmaceuticals. In other words, Takeda handed Millennium shareholders a 53% profit over the previous day's closing price. These deals will only get more frequent as Big Pharma gets more desperate. That's why I love biotech stocks for the long term...

The problem with this long-term thesis is that biotech stocks in general have been "dead in the water" for the past few years. The sector enjoyed a big run from 2003 to 2005. It's taken time to digest those gains... and money managers have been more focused on commodities since then.

But I think this "dead money" period may be ending...

In the past month, biotech was one of the few sectors to show positive returns. Oil stocks, financial stocks, and consumer-spending stocks have been killed. Many biotech stocks, on the other hand, are doing well. As Brian Hunt mentioned in yesterday's Market Notes, the S&P Biotech ETF just hit a new high for the year.

There's a good reason for this strength. A struggling economy won't hurt biotech and medical as much as, say, an automaker, retailer, or restaurant chain... And biotech is one of the few industries showing solid sales growth.

A big holding in the S&P Biotech ETF, Gilead Sciences, just reported a 22% increase in quarterly sales growth. A slew of big biotech players report earnings next week, and I expect more great numbers.

Related Articles

Biotech Is Setting Up for Another 1,347% Rally

How to Collect "Knock Out" Fees from Big Pharma

Several ETFs give you broad exposure to biotech. Just enter "biotech" in the search box on www.etfconnect.com for a full list of funds. (A warning on the HOLDRs Biotech ETF – I'd avoid it... It's ridiculously weighted toward just four high-profile companies.)

The really huge gains in biotech will be made with the best individual companies. Pick the right one and you could easily multiply your money by four or five times.

Whichever route you choose, I encourage you to pay attention to the biotech sector. It has a terrific long-term outlook and it's getting started on another run higher.

Good investing,

Rob

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$69,000,000,000

Amount of market cap lost by ExxonMobil in the past two months. Shares in America's largest company have fallen from $94 to $81 since May.

The Decade's Most Irresistible Opportunity... Don't Hesitate
By Dr. Steve Sjuggerud
July 18, 2008

Just recently, the "Investors Intelligence" poll found that professional investors are more bearish than they've been at any time in the last decade... Whenever investors get really bearish, stocks are generally near a short-term bottom.

Read On...

How Americans Should React to the Fannie Mae Bailout
By Porter Stansberry

July 17, 2008

I'm certain the government will do whatever it takes to ensure Fannie and Freddie continue to operate – but that doesn't mean bailing out the shareholders...

Read On...

This Gadget Will Revolutionize Our Power Supply
By Tom Dyson
July 16, 2008

According to the North American Reliability Corporation, United States demand for peak electricity will increase by 135 gigawatts over the next decade...

But supply will only rise by 77 gigawatts. If these projections are correct, there will be a major shortage of electricity within the next 10 years...

Read On...

The Best-Performing Stock Manager in America This Year
By Dr. Steve Sjuggerud

July 15 , 2008 8

Back in 1980, contrary to every other prognosticator out there, Leuthold was optimistic. He predicted inflation would fall to 3%. He predicted oil prices would calm down. And he predicted stocks and bonds would perform well. It was just brilliant stuff.

Read On...

A Visit to the World's Next Agricultural Superpower
By Tom Dyson

July 14, 2008

The world's largest agricultural firms all have operations in Brazil's soybean complex. I saw operations owned by Archer Daniels Midland, Bunge, Monsanto, Syngenta, John Deere, and many others.

Read On...

Gold (EOD)/Harley Davidson
AN UPDATE ON THE GOLD/HOG RATIO

Around Thanksgiving last year, we presented one of my favorite measures of real assets vs. landfill stuffing... the gold/hog ratio.

This ratio measures the performance of hard assets (represented by gold) vs. consumer "stuff" that will end up in a landfill someday (represented by the share price of Harley-Davidson, ticker: HOG).

Back then, the gold/hog ratio was 17 and rising in favor of gold. Now, that ratio is around 26. Gold is climbing as investors flee to real assets, and HOG is falling as consumers flee from expensive toys.

If you bought gold at the start of 2007, you're
50% richer. If you bought HOG shares at the start
of 2007, you're 45% poorer. Right now, folks are
much more likely to buy real assets than a motorcycle.


– Brian Hunt

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